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[米索前列醇在口腔颌面外科预防非甾体抗炎药所致胃病中的应用]

[The use of misoprostol in prevention of gastric disease from nonsteroidal anti-inflammatory drugs in oral-maxillofacial surgery].

作者信息

Bocca M, Giordano M, Del Pizzo M, Nelken A, Ghiggia M, Pomatto E

机构信息

Università degli Studi di Torino.

出版信息

Minerva Ortognatod. 1990 Apr-Jun;8(2):139-41.

PMID:2126183
Abstract

The results of a clinical experiment with a new synthetic prostaglandin for the prevention of gastric lesions induced by NSAID: the misoprostol have reported. Twenty patients were treated with this drug and the results were compared to those obtained with the use of ranitidine in the same number of patients. The clinical experiment showed an excellent misoprostol-induced gastric protection which compared to ranitidine presents the advantage of a multiple and pathogenetically oriented action mechanism.

摘要

一种用于预防非甾体抗炎药(NSAID)引起的胃部病变的新型合成前列腺素(米索前列醇)的临床实验结果已被报道。二十名患者接受了这种药物治疗,并将结果与相同数量使用雷尼替丁的患者所获得的结果进行了比较。临床实验表明,米索前列醇对胃具有极佳的保护作用,与雷尼替丁相比,它具有多方面且针对发病机制的作用机制优势。

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