Aortic stenosis in a patient with Hurler's syndrome after bone marrow transplantation.
作者信息
Watanabe Naruhito, Anagnostopoulos Petros V, Azakie Anthony
机构信息
Department of Surgery, Division of Pediatric Cardiac Surgery, UCSF Benioff Children's Hospital, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.
出版信息
Cardiol Young. 2011 Jun;21(3):349-50. doi: 10.1017/S1047951110002015. Epub 2011 Jan 25.
We describe a case of severe aortic stenosis in a 16-year-old male with Hurler's syndrome who had prior bone marrow transplantation. The excised aortic valve leaflets showed characteristic pathologic findings of Hurler's syndrome. This is the first case report of aortic valve replacement in a patient with Hurler's syndrome treated with bone marrow transplantation that demonstrates progression of the aortic valve disease despite treatment.
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