Raabe F, Janz S, Wolff G
Institut für Klinische Immunologie, Karl-Marx-Universität, Leipzig, DDR.
J Basic Microbiol. 1990;30(6):435-42. doi: 10.1002/jobm.3620300614.
Various non-ionic surfactants affect the SOS-inducing potency (SOSIP) of the model genotoxin, 4-nitroquinoline-1-oxide, in Escherichia coli PQ37 to varying degrees, as measured by an automated version of the SOS chromotest. While there is little effect on the SOSIP value and other test parameters from Tween 20 and 80 and, with some reservation, Triton X305 and Tyloxapol, over the critical micelle concentration range, the SOSIP value increases in the presence of comparable concentrations of Triton X15, 45 and 100. A possible dependence of the tester strain's beta-galactosidase production and its growth inhibition on the HLB of the non-ionic surfactants added is discussed.
通过SOS显色试验的自动化版本测定，各种非离子表面活性剂对模式基因毒素4-硝基喹啉-1-氧化物在大肠杆菌PQ37中的SOS诱导能力（SOSIP）有不同程度的影响。在临界胶束浓度范围内，吐温20和80以及在一定程度上的 Triton X305和Tyloxapol对SOSIP值和其他测试参数影响很小，而在存在相当浓度的Triton X15、45和100时，SOSIP值会增加。文中讨论了受试菌株β-半乳糖苷酶的产生及其生长抑制对所添加非离子表面活性剂亲水亲油平衡（HLB）的可能依赖性。
