Diagnostic Imaging, The Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI 02903, USA .
Cancer J. 2011 Jan-Feb;17(1):33-7. doi: 10.1097/PPO.0b013e318209176f.
Surgical resection remains the treatment of choice for patients with early-stage non-small cell lung cancer. However, some patients are not surgical candidates because of medical problems. Therefore, alternative therapies are considered in these medically inoperable patients. Radiofrequency ablation has been used clinically for more than 12 years, with many studies reporting its safety and efficacy. Because there are no large prospective clinical trials comparing the efficacy and long-term survival of the different treatment modalities, the choice of therapy is often based on a combination of tumor location, available technology and expertise, and patient preference. Here we review the principles, procedure, follow up, and clinical outcomes published to date on radiofrequency ablation in the treatment of early-stage non-small cell lung cancer.
手术切除仍然是早期非小细胞肺癌患者的首选治疗方法。然而，由于存在医疗问题，一些患者不适合手术。因此，对于这些不能手术的患者，会考虑其他替代疗法。射频消融术已在临床上应用超过 12 年，多项研究报告了其安全性和有效性。由于目前尚无大型前瞻性临床试验比较不同治疗方法的疗效和长期生存率，因此治疗方案的选择通常基于肿瘤位置、现有技术和专业知识以及患者偏好的综合考虑。本文回顾了射频消融术治疗早期非小细胞肺癌的原理、操作程序、随访和临床结果。
