Reddy M S, Jayaprada P, Rao K V
Department of Marine Zoology, S.V. University P.G. Center, Kavali, India.
Biochem Int. 1990 Oct;22(1):189-98.
The acetylcholinesterase activity in selected tissues of prawn, Metapenaeus monoceros showed a significant inhibition during commercial (CgC) and technical (TgC) grade carbaryl exposure. The rate of inhibition of AChE in nervous and non-nervous tissues is more under CgC over TgC exposure, suggests the involvement of emulsifier system for easy penetration of CgC molecule, which is absent in TgC. A progressive recovery of AChE activity from TgC and CgC induced inhibition was in the tissues within 10 days after the transfer of prawns to toxicant free water i.e., recovery or reclamation period. From the study, it has been observed that the inhibition of AChE activity is still persists evenafter 10 days of reclamation period, gives the idea of carbaryl accumulation at the cellular level or the reclamation period is not sufficient for the restoration of normalcy of AChE activity.
在商业级(CgC)和技术级(TgC)西维因暴露期间,独角新对虾特定组织中的乙酰胆碱酯酶活性受到显著抑制。与TgC暴露相比,CgC暴露下神经组织和非神经组织中AChE的抑制率更高,这表明乳化剂系统有助于CgC分子的轻松渗透,而TgC中不存在该系统。在将对虾转移到无毒水中后的10天内,即恢复或回收期间,组织中被TgC和CgC诱导抑制的AChE活性逐渐恢复。从研究中可以观察到,即使在回收期10天后,AChE活性的抑制仍然存在,这表明西维因在细胞水平上有积累,或者回收期不足以恢复AChE活性的正常状态。