Department of Psychological Studies, The Hong Kong Institute of Education, Tai Po, Hong Kong.
Pain Med. 2011 Feb;12(2):246-59. doi: 10.1111/j.1526-4637.2010.01044.x. Epub 2011 Jan 25.
The objective of this study was to examine the associations between chronic pain and psychiatric morbidity using interview-based assessments of psychiatric symptomatology. We compared the prevalence of common mental disorder (CMD; consistent with neurotic and somatic symptoms, fatigue, and negative affect), depression, and anxiety disorder(s), and associated factors with these psychiatric illnesses among Chinese patients with chronic pain attending specialist orthopedics clinic and multidisciplinary pain clinic.
A total of 370 patients with chronic pain were recruited from an Orthopedics Clinic (N=185) and a Pain Clinic (N=185) in Hong Kong. Psychiatric morbidity was assessed using the Revised Clinical Interview Schedule. Individual scores for neurotic symptoms and neurotic disorders (including depression and four types of anxiety disorders) were also calculated.
The reported lifetime prevalence rates of CMD were 35.3% and 75.3% for the Orthopedics and Pain Clinic samples, respectively. Rates of depression and anxiety disorders in the Pain Clinic (57.1% and 23.2%, respectively) were significantly higher than those in the Orthopedics sample (20.2% and 5.9%, respectively) (all P<0.001). Pain characteristics including number of pain sites, pain duration, pain intensity, and pain interference were all significantly associated with psychiatric morbidity after controlling for sociodemographic factors. Pain duration and litigation/compensation status consistently predicted concurrent pain intensity and disability.
Chronic pain is associated with psychiatric morbidity. The higher rate of depression than anxiety disorder(s) among patients with chronic pain is consistent with previous studies that have found depression to be highly prevalent in chronic pain.
本研究旨在通过基于访谈的精神症状评估来研究慢性疼痛与精神疾病之间的关联。我们比较了在香港骨科诊所(N=185)和多学科疼痛诊所(N=185)就诊的慢性疼痛患者中常见精神障碍(CMD;符合神经症和躯体症状、疲劳和负性情绪)、抑郁症和焦虑症的患病率,以及这些精神疾病的相关因素。
共招募了 370 名慢性疼痛患者,他们分别来自骨科诊所(N=185)和疼痛诊所(N=185)。使用修订后的临床访谈时间表评估精神疾病发病率。还计算了神经质症状和神经质障碍(包括抑郁症和四种焦虑症)的个体评分。
骨科诊所和疼痛诊所的终生 CMD 患病率分别为 35.3%和 75.3%。疼痛诊所的抑郁症和焦虑症患病率(分别为 57.1%和 23.2%)显著高于骨科诊所(分别为 20.2%和 5.9%)(均 P<0.001)。疼痛特征,包括疼痛部位数量、疼痛持续时间、疼痛强度和疼痛干扰,在控制社会人口统计学因素后,均与精神疾病发病相关。疼痛持续时间和诉讼/赔偿状况始终预测了疼痛强度和残疾的并存。
慢性疼痛与精神疾病发病率相关。与慢性疼痛患者中焦虑症患病率相比,抑郁症患病率更高,这与先前发现抑郁症在慢性疼痛中普遍存在的研究结果一致。