Suppr超能文献

先天性马蹄内翻足的围产儿结局。

Perinatal outcome of prenatally diagnosed congenital talipes equinovarus.

机构信息

Centre for Fetal and Maternal Medicine, Queen Charlotte's and Chelsea Hospital, Imperial College London, London W12 0HS, UK.

出版信息

Prenat Diagn. 2011 Feb;31(2):142-5. doi: 10.1002/pd.2655. Epub 2011 Jan 3.

Abstract

OBJECTIVE

The purpose of this study was to investigate the perinatal outcome of prenatally diagnosed congenital talipes equinovarus.

METHODS

This was a retrospective observational study of all cases of prenatally diagnosed congenital talipes equinovarus referred to a major tertiary fetal medicine unit. Cases were identified from the fetal medicine and obstetric databases and pregnancy details and delivery outcome data obtained. Details of termination of pregnancy, number of patients undergoing karyotyping as well as details of prenatal classification of severity were recorded.

RESULTS

A total of 174 cases were identified. Of these, outcome data was available for 88.5% (154/174) of the pregnancies. Eighty three (47.7%) of cases were isolated and 91 cases (52.3%) were associated with additional abnormalities. There was a significant difference in birth weights between the two cohorts. Bilateral abnormality tended to be more severe. A high caesarean section rate was noted overall and a high preterm delivery rate seen in the isolated group.

CONCLUSION

This study is important because it provides contemporary data that can be used to counsel women prenatally. In particular, the raised risk of preterm delivery and caesarean section as well as the increased severity of the condition when both feet are affected should be discussed. The poor perinatal outcome when additional anomalies are present and the increased risk of aneuploidy are also important factors.

摘要

目的

本研究旨在探讨产前诊断先天性马蹄内翻足的围产结局。

方法

这是一项对所有转诊至一家主要三级胎儿医学单位的产前诊断先天性马蹄内翻足病例进行的回顾性观察性研究。从胎儿医学和产科数据库中确定病例,并获取妊娠详细信息和分娩结局数据。记录了终止妊娠的病例数、进行染色体核型分析的患者数以及产前严重程度分类的详细信息。

结果

共确定了 174 例病例。其中,88.5%(154/174)的妊娠结局数据可用。83 例(47.7%)为孤立性病例,91 例(52.3%)为合并其他异常病例。两组的出生体重存在显著差异。双侧异常往往更严重。总体剖宫产率较高,孤立性组早产率较高。

结论

本研究很重要,因为它提供了可用于孕妇产前咨询的当代数据。特别是,当双脚都受累时,早产和剖宫产的风险增加以及病情严重程度增加的情况应予以讨论。存在其他异常和非整倍体风险增加的不良围产结局也是重要因素。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验