Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine and the Texas Children's Fetal Center, Texas Children's Hospital, Houston, TX, USA.
Prenat Diagn. 2011 Feb;31(2):176-80. doi: 10.1002/pd.2673. Epub 2011 Jan 4.
To assess serial changes in the Tei index of the recipient fetus secondary to fetoscopic laser photocoagulation of placental anastomoses (FLP) for twin-twin transfusion syndrome (TTTS) during the peri-operative period.
A prospective study of cases that underwent FLP at the Texas Children's Fetal Center was performed. Mean and individual changes in the Tei index measurements were obtained during the pre-operative, intra-operative and the post-operative (12-h and 24-h) periods after surgery and were compared using paired t-test. A p-value of < 0.05 was considered as significant.
A total of 20 patients were included in the study. In both the right and the left side, the mean Tei indices appeared to be increased from baseline during the intra-operative period, with a subsequent decrease to pre-operative values within 24 h of laser surgery. These changes were also noted when individualized patient results were analyzed in a serial fashion.
FLP results in a transient increase in the intra-operative myocardial performance index in the recipient fetus. These changes appear to resolve in the post-operative period.
评估胎儿镜激光凝固胎盘吻合术（FLP）治疗双胎输血综合征（TTTS）围手术期胎儿心肌 Tei 指数的系列变化。
对在德克萨斯儿童胎儿中心接受 FLP 的病例进行前瞻性研究。在术前、术中及术后（术后 12 小时和 24 小时）期间获得 Tei 指数测量的平均值和个体变化，并使用配对 t 检验进行比较。p 值<0.05 被认为具有统计学意义。
共有 20 例患者纳入研究。在右侧和左侧，Tei 指数均值在术中期间似乎从基线增加，随后在激光手术后 24 小时内降至术前值。当以连续方式分析个体化患者结果时，也观察到了这些变化。
FLP 导致受体胎儿术中心肌性能指数一过性增加。这些变化在术后期间似乎得到解决。
