Hugh S C, Enepekides D, Wong J, Yeung R, Lin V Y W
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
J Laryngol Otol. 2011 May;125(5):528-32. doi: 10.1017/S0022215110002926. Epub 2011 Jan 27.
We describe the first published case of papillary thyroid carcinoma metastatic to the temporal bone.
A 64-year-old woman presented with a large left temporal bone mass centred in the jugular foramen, initially thought to be a paraganglioma or schwannoma. She was simultaneously being investigated for a left-sided thyroid nodule, which was found to be unremarkable on repeated fine needle aspiration cytology. A biopsy of the temporal bone mass indicated that it was of thyroid origin. The patient underwent total thyroidectomy, which enabled a final diagnosis of follicular-variant papillary thyroid carcinoma with metastasis to the temporal bone.
Although biopsy is not the usual management for many types of temporal bone mass, pathological investigation is recommended if the tumour has an atypical growth rate, location, spread and/or radiological features. Metastasis of papillary thyroid carcinoma to the skull base is extremely rare, and correct diagnosis is essential in order to pursue an effective treatment plan.
我们描述首例已发表的甲状腺乳头状癌转移至颞骨的病例。
一名64岁女性，左侧颞骨有一以颈静脉孔为中心的巨大肿物，最初认为是副神经节瘤或神经鞘瘤。她同时因左侧甲状腺结节接受检查，多次细针穿刺细胞学检查显示该结节无异常。颞骨肿物活检表明其起源于甲状腺。患者接受了甲状腺全切术，最终诊断为滤泡型甲状腺乳头状癌伴颞骨转移。
尽管活检并非许多类型颞骨肿物的常规处理方法，但如果肿瘤生长速度、位置、扩散和/或影像学特征不典型，建议进行病理检查。甲状腺乳头状癌转移至颅底极为罕见，正确诊断对于制定有效的治疗方案至关重要。
