Gabalec Filip, Svilias Ioannis, Plasilova Ivana, Hovorkova Eva, Ryska Aler, Horacek Jiri
Departments of *Internal Medicine IV †Pediatrics ‡The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Králové, Czech Republic.
J Pediatr Hematol Oncol. 2014 Mar;36(2):e94-6. doi: 10.1097/MPH.0000000000000036.
In this study, we describe a case of papillary carcinoma in a 15-year-old girl who presented with a hyperfunctioning (hot) thyroid nodule and discuss it in the context of current management guidelines for patients with thyroid nodules. In adults, hot nodules rarely require cytologic or histologic evaluation, and hyperthyroidism is often treated with radioiodine (131I). However, in children and adolescents, the malignancy rate for nodules (both cold and hot) is higher and surgery is often necessary. Surgery may serve as a therapy, as well as a diagnostic tool, to treat hot nodules in children and adolescents.
在本研究中，我们描述了一名15岁女孩患乳头状癌的病例，该女孩表现为甲状腺功能亢进（热）结节，并根据当前甲状腺结节患者的管理指南进行讨论。在成人中，热结节很少需要进行细胞学或组织学评估，甲亢通常用放射性碘（131I）治疗。然而，在儿童和青少年中，结节（冷结节和热结节）的恶性率更高，通常需要手术治疗。手术可作为治疗儿童和青少年热结节的一种治疗方法以及诊断工具。
