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基于光学Scheimpflug图像的青光眼前房形态测量

Glaucoma anterior chamber morphometry based on optical Scheimpflug images.

作者信息

Alonso Ruiz Simonato, Ambrósio Junior Renato, Paranhos Junior Augusto, Sakata Lisandro Massanori, Ventura Marcelo Palis

机构信息

Department of Ophthalmology, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil.

出版信息

Arq Bras Oftalmol. 2010 Nov-Dec;73(6):497-500. doi: 10.1590/s0004-27492010000600005.

DOI:10.1590/s0004-27492010000600005
PMID:21271022
Abstract

PURPOSE

To compare the performance of gonioscopy and noncontact morphometry with anterior chamber tomography (High Resolution Pentacam - HR) using optical Scheimpflug images in the evaluation of the anterior chamber angle (ACA).

METHODS

Transversal study. 112 eyes from 74 subjects evaluated at the Glaucoma Department, Fluminense Federal University, underwent gonioscopy and Pentacam HR. Using gonioscopy, the ACA was graded using the Shaffer Classification (SC) by a single experienced examiner masked to the Pentacam HR findings. Narrow angle was determined in eyes in which the posterior trabecular meshwork could not be seen in two or more quadrants on non-indentation gonioscopy (SC Grade 2 or less). Pentacam HR images of the nasal and temporal quadrants were evaluated by custom software to automatically obtain anterior chamber measurements, such as: anterior chamber angle (ACA), anterior chamber volume (ACV) and anterior chamber depth (ACD).

RESULTS

Based on gonioscopy results, 74 (60.07%) eyes of patients classified as open-angle (SC 3 and 4) and 38 (33.93%) eyes of patients classified as narrow-angle (SC 1 and 2). Noncontact morphometry with Scheimpflug images revealed a mean ACA of 39.20 ± 5.31 degrees for open-angle and 21.18 ± 7.98 degrees for narrow-angle. The open-angle group showed significant greater ACV and ACD values when compared to narrow-angle group (ACV of 193 ± 36 mm³ vs. 90 ± 25 mm³, respectively, p<0.001; and ACD of 3,09 ± 0,42 mm vs. 1,55 ± 0,64 mm, respectively, p<0.0001.). In screening eyes with open-angle and narrow-angle with the Pentacam ACA of 20º (SC Grade 2) using the ROC curves, the analysis showed 52.6% of sensitivity and 100% of specificity.

CONCLUSIONS

The Pentacam showed ability in detecting eyes at risk for angle closure analyzing ACV and ACD.

摘要

目的

比较前房角镜检查和非接触式形态测量法与使用光学Scheimpflug图像的前房断层扫描(高分辨率Pentacam - HR)在评估前房角(ACA)方面的性能。

方法

横向研究。来自弗卢米嫩塞联邦大学青光眼科的74名受试者的112只眼睛接受了前房角镜检查和Pentacam HR检查。使用前房角镜检查,由一名对Pentacam HR检查结果不知情的经验丰富的检查者根据Shaffer分类法(SC)对ACA进行分级。在非压陷式前房角镜检查中,在两个或更多象限中看不到后小梁网的眼睛(SC分级为2级或更低)被判定为窄角。通过定制软件评估鼻侧和颞侧象限的Pentacam HR图像,以自动获得前房测量值,如:前房角(ACA)、前房容积(ACV)和前房深度(ACD)。

结果

根据前房角镜检查结果,74只(60.07%)患者的眼睛被分类为开角(SC 3和4),38只(33.93%)患者的眼睛被分类为窄角(SC 1和2)。使用Scheimpflug图像的非接触式形态测量法显示,开角眼的平均ACA为39.20±5.31度,窄角眼为21.18±7.98度。与窄角组相比,开角组的ACV和ACD值显著更高(ACV分别为193±36 mm³和90±25 mm³,p<0.001;ACD分别为3.09±0.42 mm和1.55±0.64 mm,p<0.0001)。使用ROC曲线,以20°的Pentacam ACA(SC分级为2级)筛查开角和窄角眼时,分析显示敏感性为52.6%,特异性为100%。

结论

Pentacam在通过分析ACV和ACD检测有闭角风险的眼睛方面表现出能力。

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