Dembski Michał, Nowińska Anna, Ulfik-Dembska Klaudia, Wylęgała Edward
Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Ophthalmology Department, Railway Hospital in Katowice, 40-760 Katowice, Poland.
J Clin Med. 2021 Mar 5;10(5):1094. doi: 10.3390/jcm10051094.
The present study determined the mean reference values of the anterior segment parameters of the selected eye using swept source optical coherence tomography (SS-OCT) in healthy Caucasian participants.
A total of 166 volunteers (age 54-79 years), women ( = 92) and men ( = 74), were analyzed. One eye of each subject was randomly selected for anterior segment imaging. The anterior segment of the eye was scanned with CASIA2. The analyzed anterior segment parameters were divided into three groups, namely parameters of the cornea, lens, and angle.
The OCT (e.g., Ks, Kf, pKf, pKs, and central corneal thickness) and Fourier parameters of the cornea were significantly different between females and males. The iridocorneal angle was the smallest in the upper quadrant for all distance from the apex of the angle (250, 500, and 750 µm).
Therefore, SS-OCT enables the analysis of parameters of the cornea, anterior chamber, lens, and iridocorneal angle, highlighting its clinical utility. Sex-specific differences in the analyzed parameters should be taken into account during the diagnosis of corneal diseases. The configuration of the filtration angle is an important marker during glaucoma diagnosis and drainage implant surgery. Measurements with CASIA 2is characterized by very good repeatability.
本研究使用扫频光学相干断层扫描（SS-OCT）测定了健康白种人参与者所选眼睛前段参数的平均参考值。
共分析了166名志愿者（年龄54 - 79岁），其中女性92名，男性74名。为每位受试者的一只眼睛随机进行前段成像。使用CASIA2对眼睛前段进行扫描。所分析的前段参数分为三组，即角膜、晶状体和房角的参数。
角膜的OCT参数（如Ks、Kf、pKf、pKs和中央角膜厚度）和傅里叶参数在女性和男性之间存在显著差异。对于距房角顶点的所有距离（250、500和750 µm），虹膜角膜角在上象限最小。
因此，SS-OCT能够分析角膜、前房、晶状体和虹膜角膜角的参数，凸显了其临床实用性。在角膜疾病诊断过程中应考虑所分析参数的性别差异。滤过角的形态是青光眼诊断和引流植入手术中的一个重要指标。使用CASIA 2进行测量具有非常好的重复性。
