Almeida Patricia Pinheiro de, Sanches Seisse Gabriela Gandolfi, Carvallo Renata Mota Mamede
Faculdade de Medicina, Universidade de São Paulo.
Pro Fono. 2010 Oct-Dec;22(4):409-14. doi: 10.1590/s0104-56872010000400008.
Distortion product otoacoustic emission measures (DPOAE) verifies, among other characteristics, the emergence and growth rate of the DPOAE response according to sound stimulus intensity (growth curve).
To estimate the DPOAE threshold in neonates according to the DPOAE growth curve at 2 kHz and 4 kHz, with stimulus presentation ranging between 35 and 70 dB SPL.
Participants were 51 neonates, with 24 to 84 hours of life and with no indication of risk for hearing impairment. The DPOAE were registered in the growth curve function at 2 kHz and at 4 kHz. Neonates were evaluated during the period of hospital stay, after birth. Three possible thresholds were considered (LIM 1, LIM 2 and LIM 3) based on the presence of response at 3 dB SPL in the signal to noise ratio.
The average thresholds intensities ranged from 47.55 to 49.85 dB at 2 kHz and from 55.52 to 59.94 dB at 4 kHz. The mean amplitude response ranged from 6.67 to 8.27 dB at 2 kHz and from 6.99 to 11.35 dB at 4 kHz. There was significant difference between the three thresholds for the two studied frequencies.
The procedure was feasible for the neonatal population revealing mean thresholds of up to 60 dB for both frequencies. Even though participants presented elevated thresholds, robust amplitude responses were observed.
畸变产物耳声发射测量（DPOAE）除其他特征外，还根据声音刺激强度验证DPOAE反应的出现和增长率（增长曲线）。
根据2kHz和4kHz的DPOAE增长曲线，在35至70dB SPL的刺激呈现范围内估计新生儿的DPOAE阈值。
研究对象为51名新生儿，出生24至84小时，无听力障碍风险迹象。在2kHz和4kHz的增长曲线函数中记录DPOAE。新生儿在出生后的住院期间接受评估。根据信噪比中3dB SPL处的反应情况，考虑了三个可能的阈值（LIM 1、LIM 2和LIM 3）。
2kHz时平均阈值强度范围为47.55至49.85dB，4kHz时为55.52至59.94dB。2kHz时平均幅度反应范围为6.67至8.27dB，4kHz时为6.99至11.35dB。两个研究频率的三个阈值之间存在显著差异。
该程序对新生儿群体可行，两个频率的平均阈值高达60dB。尽管参与者的阈值升高，但观察到了较强的幅度反应。
