Department of Urology, Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Int J Urol. 2011 Feb;18(2):171-4. doi: 10.1111/j.1442-2042.2010.02685.x. Epub 2010 Dec 22.
The aim of the present study was to assess the treatment outcomes in a cohort of adult patients with intratesticular rhabdomyosarcoma. Between 1999 and 2008, 296 patients underwent radical orchiectomy for intrascrotal mass. A retrospective chart review was carried out for adult patients diagnosed with intratesticular rhabdomyosarcoma. Overall, six patients (mean age 21 years, range 17-23) were included: five had embryonic rhabdomyosarcoma and one had pleomorphic rhabdomyosarcoma. Four patients underwent retroperitoneal lymph node dissection and five patients had postoperative chemotherapy. The mean length of follow up was 28 months (range 12-51 months). One patient was lost to follow up after 26 months, five cases remained alive at the end of the study. Surgical resection with chemotherapy was an effective way to achieve favorable outcomes and long-term survival in adult patients with metastases from intratesticular rhabdomyosarcoma.
本研究旨在评估一组睾丸内横纹肌肉瘤成年患者的治疗结果。1999 年至 2008 年间，296 例患者因阴囊内肿块行根治性睾丸切除术。对诊断为睾丸内横纹肌肉瘤的成年患者进行了回顾性病历审查。共有 6 名患者（平均年龄 21 岁，范围 17-23 岁）入选：5 例为胚胎性横纹肌肉瘤，1 例为多形性横纹肌肉瘤。4 例患者行腹膜后淋巴结清扫术，5 例患者术后化疗。平均随访时间为 28 个月（范围 12-51 个月）。1 例患者在 26 个月后失访，5 例患者在研究结束时仍存活。对于睾丸内横纹肌肉瘤转移的成年患者，手术切除联合化疗是实现良好疗效和长期生存的有效方法。
