Gamba P G, Cecchetto G, Katende M, Carli M, Sotti G, Guglielmi M
Eur J Pediatr Surg. 1994 Jun;4(3):158-60. doi: 10.1055/s-2008-1066091.
This study is based on the experience of the Italian Cooperative Studies "AIEOP-RMS 79 and RMS 88". Between October 1979 and December 1989 299 children under 15 years of age with a histologically proven rhabdomyosarcoma (RMS) were examined. We analyzed the problem of the paratesticular localization paying particular attention to the role of surgery in dealing with paraaortic nodes. In the first study (RMS 79) the surgical exploration of retroperitoneal nodes was required: this procedure performed in 11 out of 14 patients affected by paratesticular RMS confirmed the negative data observed with diagnostic investigations. In RMS 88 study the sampling of retroperitoneal nodes was not required in cases with negative radiological findings but suggested in those cases with uncertain signs; two out of 8 patients underwent a laparotomy. In these two cases the results were negative. These 22 children were treated with an adjuvant chemotherapy after surgery and at present they show no evidence of disease.
本研究基于意大利合作研究“AIEOP-RMS 79和RMS 88”的经验。在1979年10月至1989年12月期间，对299名15岁以下经组织学证实患有横纹肌肉瘤（RMS）的儿童进行了检查。我们分析了睾丸旁定位问题，特别关注手术在处理腹主动脉旁淋巴结方面的作用。在第一项研究（RMS 79）中，需要对腹膜后淋巴结进行手术探查：在14例睾丸旁RMS患者中，有11例进行了该手术，证实了诊断性检查所观察到的阴性数据。在RMS 88研究中，对于放射学检查结果为阴性的病例，不需要对腹膜后淋巴结进行取样，但对于体征不确定的病例则建议取样；8例患者中有2例接受了剖腹手术。在这两个病例中，结果均为阴性。这22名儿童在手术后接受了辅助化疗，目前未显示出疾病迹象。
