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通过胎儿腹部心电图理解先天性心脏缺陷:病例报告及临床意义

Understanding congenital heart defects through abdominal fetal electrocardiography: case reports and clinical implications.

作者信息

Velayo Clarissa, Sato Naoaki, Ito Takuya, Chisaka Hiroshi, Yaegashi Nobuo, Okamura Kunihiro, Kimura Yoshitaka

机构信息

Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

出版信息

J Obstet Gynaecol Res. 2011 May;37(5):428-35. doi: 10.1111/j.1447-0756.2010.01367.x. Epub 2011 Jan 27.

Abstract

AIMS

Congenital heart defects are the most common fetal structural anomalies of which a significant number remain unrecognized during postnatal life. Fetal electrocardiography (FECG) is an ideal clinical tool to complement ultrasonography for the screening and management of these cases where early and accurate diagnoses would allow definite rather than palliative treatment. The objective of this report was to correlate the particular FECG results found with the different types of congenital heart defects involved and to further demonstrate the usefulness of FECG in clinical settings.

MATERIAL & METHODS: This is a report of four cases of prenatally diagnosed congenital heart defects seen at a university hospital in Sendai, Japan. Their complete and thorough evaluation included, among other tests, abdominal FECG analysis.

RESULTS

The presence of premature ventricular contractions, a prolonged pre-ejection period (PEP > 75 msec), and prolonged QTc intervals (QTc > 440 msec) served as markers of hemodynamic alteration but were unlikely determinants of disease severity precluding further investigation.

CONCLUSIONS

In practice, similar findings found on FECG should raise the index of suspicion for the presence of congenital heart disease and prompt a targeted ultrasound scan.

摘要

目的

先天性心脏缺陷是最常见的胎儿结构异常,其中相当一部分在出生后仍未被识别。胎儿心电图(FECG)是一种理想的临床工具,可补充超声检查,用于筛查和管理这些病例,早期准确诊断可实现确定性而非姑息性治疗。本报告的目的是将特定的FECG结果与所涉及的不同类型先天性心脏缺陷相关联,并进一步证明FECG在临床环境中的实用性。

材料与方法

这是一份关于日本仙台一家大学医院产前诊断的4例先天性心脏缺陷病例的报告。对其进行的全面彻底评估包括腹部FECG分析等多项检查。

结果

室性早搏、射血前期延长(PEP>75毫秒)和QTc间期延长(QTc>440毫秒)可作为血流动力学改变的指标,但不太可能是疾病严重程度的决定因素,无需进一步调查。

结论

在实际操作中,FECG上发现的类似结果应提高对先天性心脏病存在的怀疑指数,并促使进行针对性的超声扫描。

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