Shimizu Yoshihiko, Yamaguchi Wakasa, Takashima Akiko, Kaku Shoji, Kita Nobuyuki, Murakami Takashi
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Ohtsu, Shiga, Japan.
J Obstet Gynaecol Res. 2011 May;37(5):412-5. doi: 10.1111/j.1447-0756.2010.01369.x. Epub 2011 Jan 27.
Laparoscopy has been performed in women with unexplained infertility, but the recent trend is to commence in vitro fertilization (IVF) without prior laparoscopy. The aim of this study was to determine whether or not laparoscopic surgery is necessary for these patients.
MATERIAL & METHODS: With a diagnosis of unexplained infertility, 51 women underwent laparoscopic surgery followed by IVF (laparoscopy group) and 41 women underwent IVF without prior laparoscopy (IVF group). We reviewed these two groups retrospectively and evaluated the cumulative pregnancy rate.
In the laparoscopy group, 16 of the 51 women became pregnant spontaneously soon after surgery. Twenty-three patients became pregnant with IVF. In the IVF group, 32 patients became pregnant with IVF. Two of the 41 women became pregnant spontaneously while waiting to commence IVF.
Laparoscopy should be offered as an option for younger patients who desire spontaneous pregnancy because there was no significant difference of the cumulative pregnancy rate between the groups.
腹腔镜检查已应用于不明原因不孕症的女性,但最近的趋势是在未进行腹腔镜检查的情况下直接开始体外受精(IVF)。本研究的目的是确定这些患者是否需要进行腹腔镜手术。
51例诊断为不明原因不孕症的女性接受了腹腔镜手术,随后进行体外受精(腹腔镜检查组),41例女性未进行腹腔镜检查直接接受体外受精(体外受精组)。我们对这两组进行了回顾性分析,并评估了累积妊娠率。
在腹腔镜检查组中,51例女性中有16例在手术后不久自然受孕。23例患者通过体外受精受孕。在体外受精组中,32例患者通过体外受精受孕。41例女性中有2例在等待开始体外受精期间自然受孕。
对于希望自然受孕的年轻患者,应将腹腔镜检查作为一种选择,因为两组之间的累积妊娠率没有显著差异。