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口服抗凝治疗患者结局和慢性护理管理的差异:一项探索性研究。

Differences in patient outcomes and chronic care management of oral anticoagulant therapy: an explorative study.

机构信息

TRANZO, Tilburg University, Tilburg, The Netherlands.

出版信息

BMC Health Serv Res. 2011 Jan 27;11:18. doi: 10.1186/1472-6963-11-18.

Abstract

BACKGROUND

The oral anticoagulant therapy - provided to prevent thrombosis - is known to be associated with substantial avoidable hospitalization. Improving the quality of the oral anticoagulant therapy could avoid drug related hospitalizations. Therefore, this study compared the patient outcomes between Dutch anticoagulant clinic (AC) regions taking the variation in chronic care management into account in order to explore whether chronic care management elements could improve the quality of oral anticoagulant therapy.

METHODS

Two data sources were combined. The first source was a questionnaire that was send to all ACs in the Netherlands in 2008 (response = 100%) to identify the application of chronic care management elements in the AC regions. The Chronic Care Model of Wagner was used to make the concept of chronic care management operational. The second source was the report of the Dutch National Network of ACs which contains patient outcomes of the ACs.

RESULTS

Patient outcomes achieved by the ACs were good, yet differences existed; for instance the percentage of patients in the appropriate therapeutic ranges varied from 67 to 87% between AC regions. Moreover, differences existed in the use of chronic care management elements of the chronic care model, for example 12% of the ACs had multidisciplinary meetings and 58% of the ACs had formal agreements with at least one hospital within their region. Patient outcomes were significantly associated with patient orientation and the number of specialized nurses versus doctors (p-values < 0.05). Furthermore, the overall extent to which chronic care management elements were applied was positively associated with patient outcomes (p-values < 0.05).

CONCLUSIONS

Substantial differences in the patient outcomes as well as chronic care management of oral anticoagulant therapy existed. Since our results showed a positive association between overall application of chronic care management and patient outcomes, additional research is needed to fully understand the working mechanism of chronic care management.

摘要

背景

口服抗凝治疗 - 旨在预防血栓形成 - 已知与大量可避免的住院治疗有关。改善口服抗凝治疗质量可以避免与药物相关的住院治疗。因此,本研究比较了荷兰抗凝诊所(AC)区域的患者结局,同时考虑了慢性护理管理的变化,以探讨慢性护理管理要素是否可以改善口服抗凝治疗的质量。

方法

合并了两个数据源。第一个来源是 2008 年向荷兰所有 AC 发送的问卷,以确定 AC 区域中慢性护理管理要素的应用情况(应答率为 100%)。采用 Wagner 的慢性护理模型使慢性护理管理的概念具有可操作性。第二个来源是荷兰 AC 网络的报告,其中包含 AC 的患者结局。

结果

AC 取得的患者结局良好,但存在差异;例如,AC 区域的合适治疗范围百分比在 67%至 87%之间不等。此外,慢性护理模型中的慢性护理管理要素的使用也存在差异,例如,12%的 AC 有多学科会议,58%的 AC 与所在区域内的至少一家医院有正式协议。患者结局与患者定位以及专门护士与医生的数量显著相关(p 值<0.05)。此外,慢性护理管理要素的总体应用程度与患者结局呈正相关(p 值<0.05)。

结论

口服抗凝治疗的患者结局和慢性护理管理存在很大差异。由于我们的结果显示慢性护理管理的总体应用与患者结局之间存在正相关,因此需要进一步研究以充分了解慢性护理管理的工作机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86f1/3040705/4e119145241c/1472-6963-11-18-1.jpg

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