Department of Pathology, Rhode Island Hospital, 593 Eddy Street, APC 12, Providence, RI 02903, USA.
Diagn Pathol. 2011 Jan 27;6:13. doi: 10.1186/1746-1596-6-13.
We encountered two cases of endometrioid carcinoma of uterus with extensive surface epithelial changes (SECs) mimicking serous borderline tumor (SBT) of the ovary. The first case was a well-differentiated endometrioid carcinoma arising in a background of complex atypical hyperplasia. The second case was moderately-differentiated endometrioid carcinoma with squamous and mucinous differentiation. The SECs comprised of thin microapapillae without hierarchal branching, lined by cuboidal cells with eosinophilic cytoplasm and mild to moderate nuclear atypia. These areas were reminiscent of SBTs of ovary, micropapillary type. This report expands the existing spectrum of SECs. Serous borderline tumor of ovary like surface epithelial changes could be misleading if present in an endometrial biopsy or curettings. Therefore, knowledge of this morphologic variation is important.
我们遇到了两例子宫内膜样癌，其表面上皮变化（SEC）广泛，类似于卵巢浆液性交界性肿瘤（SBT）。第一例为分化良好的子宫内膜样癌，发生于复杂非典型增生背景下。第二例为中分化子宫内膜样癌，伴鳞化和黏液分化。SEC 由无层次分支的薄微乳头组成，由嗜酸性细胞质和轻至中度核异型性的立方细胞衬覆。这些区域类似于卵巢微乳头状型 SBT。本报告扩展了 SEC 的现有范围。如果在子宫内膜活检或刮宫术中存在卵巢 SBT 样表面上皮变化，则可能会产生误导。因此，了解这种形态学变化很重要。
