磺脲类药物治疗对非胰岛素依赖型糖尿病患者胰岛素敏感性的影响。
Effect of sulphonylurea therapy on insulin sensitivity in non insulin dependent diabetics.
作者信息
Khandekar S, Sethi B K, Dash R J
机构信息
Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh.
出版信息
J Assoc Physicians India. 1990 Jul;38(7):469-71.
Insulin tolerance test was done to assess the insulin sensitivity in a group of untreated non insulin dependent diabetic subjects before and after sulfonylurea (tolbutamide, glibenclamide, glipizide) therapy. The parameters studied were KITT, slope of the blood glucose fall, summation values, and area under the curve of glucose response. All the three commonly used sulphonylurea drugs improved insulin sensitivity after 4 weeks of therapy.
对一组未经治疗的非胰岛素依赖型糖尿病患者在磺脲类药物（甲苯磺丁脲、格列本脲、格列吡嗪）治疗前后进行胰岛素耐量试验，以评估胰岛素敏感性。研究的参数包括胰岛素敏感指数（KITT）、血糖下降斜率、总和值以及葡萄糖反应曲线下面积。所有三种常用的磺脲类药物在治疗4周后均改善了胰岛素敏感性。
Zotero 插件