[一种小剂量糖尿病制剂（格列吡嗪）在急性实验中的临床疗效]
[Clinical efficacy of a Minidiab preparation (glipizide) in an acute experiment].
作者信息
Borisova A M, Taneva T, Koev D, Georgieva R
出版信息
Vutr Boles. 1988;27(2):85-9.
PMID:3137730
Abstract
The hypoglycemic action of Minidiab (Glipizide) and maninil (Glibenclamide) were studied in an acute experiment. 10 patients with type 2 diabetes mellitus (6 men and 4 women, mean age 49.1 years, were examined. The blood sugar level and the insulinemia were followed up after a 10 mg morning dose of each drug. The hypoglycemic action of both drugs is identical but is reached in different ways. Minidiab has a faster, shorter but stronger insulinotropic action. Maninil exerts a better peripheral effect.
摘要
在一项急性实验中研究了美吡达（格列吡嗪）和优降糖（格列本脲）的降血糖作用。对10例2型糖尿病患者（6例男性和4例女性，平均年龄49.1岁）进行了检查。在每天早晨服用10毫克每种药物后，对血糖水平和胰岛素血症进行了跟踪监测。两种药物的降血糖作用相同，但实现方式不同。美吡达具有更快、更短但更强的促胰岛素分泌作用。优降糖具有更好的外周效应。
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