Department of Community and Family Health, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd, MDC56, Tampa, FL 33612, United States.
Res Dev Disabil. 2011 Mar-Apr;32(2):462-9. doi: 10.1016/j.ridd.2010.12.042. Epub 2011 Jan 26.
To estimate the prevalence of cerebral palsy (CP) and the frequency of co-occurring developmental disabilities (DDs), gross motor function (GMF), and walking ability using the largest surveillance DD database in the US.
We conducted population-based surveillance of 8-year-old children in 2006 (N=142,338), in areas of Alabama, Georgia, Wisconsin, and Missouri. This multi-site collaboration involved retrospective record review at multiple sources. We reported CP subtype, co-occurring DDs, Gross Motor Function Classification System (GMFCS) level, and walking ability as well as CP period prevalence by race/ethnicity and sex.
CP prevalence was 3.3 (95% confidence interval [CI]: 3.1-3.7) per 1000 and varied by site, ranging from 2.9 (Wisconsin) to 3.8 (Georgia) per 1000, 8-year olds (p<0.02). Approximately 81% had spastic CP. Among children with CP, 8% had an autism spectrum disorder and 35% had epilepsy. Using the GMFCS, 38.1% functioned at the highest level (I), with 17.1% at the lowest level (V). Fifty-six percent were able to walk independently and 33% had limited or no walking ability.
Surveillance data are enhanced when factors such as functioning and co-occurring conditions known to affect clinical service needs, quality of life, and health care are also considered.
利用美国最大的发育障碍监测数据库，估计脑瘫（CP）的患病率以及与脑瘫共病的发育障碍（DDs）、粗大运动功能（GMF）和行走能力的发生频率。
我们对 2006 年（N=142338）8 岁儿童进行了基于人群的监测，监测地点位于阿拉巴马州、佐治亚州、威斯康星州和密苏里州。这一多站点合作涉及多个来源的回顾性记录审查。我们报告了 CP 亚型、共病 DDs、粗大运动功能分类系统（GMFCS）水平和行走能力，以及按种族/族裔和性别划分的 CP 时期患病率。
CP 的患病率为每 1000 人中有 3.3 例（95%置信区间[CI]：3.1-3.7），且各监测点之间存在差异，范围从每 1000 人 2.9 例（威斯康星州）到每 1000 人 3.8 例（佐治亚州），差异具有统计学意义（p<0.02）。大约 81%的 CP 为痉挛型。在患有 CP 的儿童中，8%患有自闭症谱系障碍，35%患有癫痫。使用 GMFCS，38.1%的儿童处于最高功能级别（I），17.1%的儿童处于最低功能级别（V）。56%的儿童能够独立行走，33%的儿童行走能力有限或无法行走。
当考虑到已知会影响临床服务需求、生活质量和医疗保健的功能和共病情况等因素时，监测数据会得到增强。
