日本大阪原发性颅内肿瘤发病率的变化趋势。

Trends in the incidence of primary intracranial tumors in Osaka, Japan.

机构信息

Department of Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Disease, 3-3 Nakamichi 1-Chome, Higashinari-ku, Osaka 537-8511, Japan.

出版信息

Jpn J Clin Oncol. 2011 Feb;41(2):291-4. doi: 10.1093/jjco/hyq204.

DOI:10.1093/jjco/hyq204

PMID:21273377

Abstract

We analyzed the trends in the age-standardized incidence rates of 10,460 cases of primary intracranial tumors diagnosed during 1975 and 2004, Osaka, Japan using the Joinpoint regression analysis. During the period 1975-2004, the age-standardized incidence rates of total intracranial tumors increased until 1987 at 3.1% per year and then decreased significantly at -1.8% per year. The time trends were different according to the age groups. In the age group 0-19, the rate did not exhibit substantial increase or decrease. In the age group 20-74, the rates increased significantly until 1988 and then leveled off until 1999 and finally decreased. Whereas in the age group 75 and over, the rates increased drastically until 1984 and then leveled off. During the recent 10 year period 1995-2004, the age-standardized incidence rates of meningioma decreased significantly, but those of glioblastoma did not.

摘要

我们使用 Joinpoint 回归分析，分析了 1975 年至 2004 年期间在日本大阪诊断的 10460 例原发性颅内肿瘤的年龄标准化发病率趋势。在 1975-2004 年期间，总颅内肿瘤的年龄标准化发病率在 1987 年之前以每年 3.1%的速度增加，然后以每年-1.8%的速度显著下降。时间趋势因年龄组而异。在 0-19 岁年龄组中，发病率没有明显的增加或减少。在 20-74 岁年龄组中，发病率直到 1988 年才显著增加，然后在 1999 年之前保持稳定，最后才下降。而在 75 岁及以上年龄组中，发病率直到 1984 年才急剧上升，然后才稳定下来。在最近的 10 年期间（1995-2004 年），脑膜瘤的年龄标准化发病率显著下降，但胶质母细胞瘤的发病率没有下降。