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万古霉素使用后发生中毒性表皮坏死松解症:病例报告并探讨其治疗管理。

Toxic epidermal necrolyis after vancomycin use: a case report and discussion of management.

机构信息

Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY 11201, USA.

出版信息

Am J Ther. 2013 Mar-Apr;20(2):223-5. doi: 10.1097/MJT.0b013e3181f94c27.

Abstract

Vancomycin is a commonly used antibiotic for severe Gram-positive bacterial infections, especially for methicillin-resistant Staphylococcus Aureus and coagulase-negative staphylococci infections. Nevertheless, only few cases of toxic epidermal necrolysis have been reported since the introduction of Vancomycin into clinical practice. We report a case of a 35-year-old man who presented with multiple facial abscesses and methicillin-resistant Staphylococcus Aureus bactermia and who was started on Vancomycin and later developed toxic epidermal necrolysis.

摘要

万古霉素是一种常用于治疗严重革兰阳性菌感染的抗生素,特别是耐甲氧西林金黄色葡萄球菌和凝固酶阴性葡萄球菌感染。然而,自从万古霉素应用于临床实践以来,仅有少数中毒性表皮坏死松解症的病例报告。我们报告了 1 例 35 岁男性,他因多发性面部脓肿和耐甲氧西林金黄色葡萄球菌菌血症而开始使用万古霉素,随后发展为中毒性表皮坏死松解症。

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