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[抗磷脂综合征患者孕中期的 HELLP 综合征]

[HELLP in the second trimester in a patient with antiphospholipid syndrome].

作者信息

Madsen Bjørn Stæhr, Havelund Troels

机构信息

Lykkeshøj 20, Munkebo, Denmark.

出版信息

Ugeskr Laeger. 2011 Jan 31;173(5):357-8.

PMID:21276403
Abstract

The syndrome of haemolysis, elevated liver enzymes and low platelets (HELLP) is estimated to occur in 0.01-0.2% of pregnancies and is considered a severe form of preeclampsia. It is associated with considerable risk of maternal and foetal mortality. HELLP syndrome associated with antiphospholipid syndrome is known to occur early in the pregnancy. We report a case of severe HELLP syndrome complicated by multiple hepatic infarctions and portal vein thrombosis in the second trimester in a patient with antiphospholipid syndrome.

摘要

溶血、肝酶升高和血小板减少综合征(HELLP)据估计在0.01%-0.2%的妊娠中发生,被认为是子痫前期的一种严重形式。它与孕产妇和胎儿死亡的相当大风险相关。已知与抗磷脂综合征相关的HELLP综合征在妊娠早期发生。我们报告一例抗磷脂综合征患者在妊娠中期发生严重HELLP综合征并伴有多发性肝梗死和门静脉血栓形成的病例。

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1
[HELLP in the second trimester in a patient with antiphospholipid syndrome].[抗磷脂综合征患者孕中期的 HELLP 综合征]
Ugeskr Laeger. 2011 Jan 31;173(5):357-8.
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Preeclampsia and liver infarction in early pregnancy associated with the antiphospholipid syndrome.子痫前期与妊娠早期肝梗死伴抗磷脂综合征
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Severe syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP) in the 18th week of pregnancy associated with the antiphospholipid-antibody syndrome.妊娠第18周时出现的严重溶血、肝酶升高和血小板减少综合征(HELLP)与抗磷脂抗体综合征相关。
Acta Obstet Gynecol Scand. 2003 Jul;82(7):679-80. doi: 10.1034/j.1600-0412.2003.00181.x.
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[Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome].[伴有早期HELLP综合征及可能的灾难性抗磷脂综合征的肝梗死]
Rev Med Interne. 2009 Mar;30(3):255-9. doi: 10.1016/j.revmed.2008.09.013. Epub 2009 Jan 7.
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Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome.抗磷脂综合征:早发型HELLP综合征的一个诱发因素。
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HELLP syndrome in pregnancies below 26th week.孕26周以下的HELLP综合征。
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Hepatic infarctions during pregnancy are associated with the antiphospholipid syndrome and in addition with complete or incomplete HELLP syndrome.妊娠期肝梗死与抗磷脂综合征相关,此外还与完全或不完全性HELLP综合征相关。
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Hepatic infarction during pregnancy in catastrophic antiphospholipid syndrome.灾难性抗磷脂综合征孕期的肝梗死
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The HELLP syndrome in the antiphospholipid syndrome: retrospective study of 16 cases in 15 women.抗磷脂综合征中的HELLP综合征:15名女性16例病例的回顾性研究
Ann Rheum Dis. 2005 Feb;64(2):273-8. doi: 10.1136/ard.2003.019000.
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Antiphospholipid syndrome during pregnancy: associated with early onset of HELLP syndrome and liver infarctions.妊娠期抗磷脂综合征:与HELLP综合征及肝梗死的早期发作相关。
Eur J Obstet Gynecol Reprod Biol. 2005 Dec 1;123(2):255-7. doi: 10.1016/j.ejogrb.2005.04.005.

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