Giaquinto S
Divisione di Rieducazione Neuromotoria, Ospedale S. Giovanni Battista, Roma.
Ann Ital Med Int. 1990 Jul-Sep;5(3 Pt 2):249-53.
Until a few years ago physicians were not rehabilitation-oriented, but recent discoveries regarding the plasticity of the nervous system have made the patient with an acute cerebrovascular lesion a clinical model of great interest. Furthermore, the severity of the frequent residual invalidities and the high social costs are the reasons why this field of medicine is becoming increasingly important. The clinical study of stroke has not changed much during the past century. Perhaps our semeiological abilities are not the same but we have improved our knowledge of the neurosciences and we know that in the acute phase we have to look towards the patient's future and not only at his current condition. A certain degree of recovery occurs immediately after stroke thanks to the resolution of secondary events such as edema and ischemia. Other factors that may have important effects on recovery include the localization, nature, extension and degree of brain damage, the patient's sex and age, the duration of coma, the patient's original cognitive capacity, his personality and motivation as well as the duration and intensity of rehabilitation and the time before starting rehabilitation. Many of these variables are difficult to check in trials performed in humans. Statistical problems make it difficult to prove any beneficial effect of rehabilitation. Some recent trials have shown statistically significant improvements attributable to rehabilitation. For instance, exercise under visual stimulation around a scotoma has been shown to reduce the area of blindness. The improvements occurred only after exercise and never spontaneously. What happens when rehabilitation favours recovery?(ABSTRACT TRUNCATED AT 250 WORDS)
直到几年前,医生们还没有以康复为导向,但最近关于神经系统可塑性的发现,使急性脑血管病变患者成为一个备受关注的临床模型。此外,频繁出现的严重残疾以及高昂的社会成本,是这一医学领域变得越来越重要的原因。在过去的一个世纪里,中风的临床研究变化不大。也许我们的症状学能力没有什么不同,但我们对神经科学的了解有所提高,而且我们知道,在急性期,我们必须关注患者的未来,而不仅仅是他目前的状况。中风后,由于水肿和缺血等继发性事件的消退,会立即出现一定程度的恢复。其他可能对恢复有重要影响的因素包括脑损伤的部位、性质、范围和程度、患者的性别和年龄、昏迷持续时间、患者原有的认知能力、他的性格和动机,以及康复的持续时间和强度,还有开始康复的时间。在人体试验中,很难对这些变量中的许多进行检测。统计问题使得难以证明康复有任何有益效果。最近的一些试验显示,康复有统计学上的显著改善。例如,在暗点周围进行视觉刺激下的运动已被证明可以减少失明面积。改善仅在运动后出现,从未自发出现。当康复促进恢复时会发生什么?(摘要截短于250字)