动物模型对理解甲型流感病毒的宿主范围和毒力的贡献。
The contribution of animal models to the understanding of the host range and virulence of influenza A viruses.
机构信息
Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892, USA.
出版信息
Microbes Infect. 2011 May;13(5):502-15. doi: 10.1016/j.micinf.2011.01.014. Epub 2011 Jan 27.
Abstract
Since ferrets were first used in 1933 during the initial isolation of influenza A viruses, animal models have been critical for influenza research. The following review discusses the contribution of mice, ferrets, and non-human primates to the study of influenza virus host range and pathogenicity.
摘要
自 1933 年首次在流感 A 病毒的初步分离中使用雪貂以来，动物模型一直是流感研究的关键。以下综述讨论了小鼠、雪貂和非人类灵长类动物对流感病毒宿主范围和致病性研究的贡献。
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