Rizzo Marco
Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA.
J Hand Surg Am. 2011 Feb;36(2):345-53. doi: 10.1016/j.jhsa.2010.11.035.
Arthritis of the metacarpophalangeal joint can result in considerable disability and pain. Inflammatory, posttraumatic, crystalline, and osteoarthritis are common etiologies of joint disease. A variety of nonsurgical treatment options have been shown to be effective, including activity modification, anti-inflammatory medications, splinting, and cortisone injections. In addition, newer generation disease-modifying antirheumatic drugs geared toward the treatment of rheumatoid arthritis have shown promise in retarding the inflammatory process. Another, relatively newer, conservative treatment option includes topical anti-inflammatories such as diclofenac sodium that are now approved by the Federal Drug Administration. Surgical treatment options most commonly include arthroplasty and arthrodesis. In the treatment of thumb metacarpophalangeal arthritis, arthrodesis is a popular and generally reliable surgical solution. In the fingers, arthroplasty remains the most common treatment option. Traditional constrained silicone joint replacements remain the most commonly used. Newer generation, unconstrained, surface replacement arthroplasties have shown promise in the treatment of osteoarthritis and select cases of inflammatory arthritis in which there is good bone stock, no or minimal deformity, adequate supporting soft tissues, and good disease control.
掌指关节关节炎可导致严重的功能障碍和疼痛。炎症性、创伤后、结晶性和骨关节炎是关节疾病的常见病因。多种非手术治疗方法已被证明有效,包括调整活动、使用抗炎药物、夹板固定和皮质类固醇注射。此外,新一代用于治疗类风湿关节炎的改善病情抗风湿药已显示出在延缓炎症过程方面的前景。另一种相对较新的保守治疗选择包括局部抗炎药,如双氯芬酸钠,现已获得美国食品药品监督管理局的批准。手术治疗方法最常见的包括关节成形术和关节融合术。在拇指掌指关节关节炎的治疗中,关节融合术是一种常用且通常可靠的手术解决方案。在手指方面,关节成形术仍然是最常见的治疗选择。传统的受限硅胶关节置换仍然是最常用的。新一代非受限表面置换关节成形术已显示出在治疗骨关节炎以及某些炎性性关节炎的特定病例中具有前景,这些病例需具备良好的骨量、无畸形或轻度畸形、足够的支持软组织以及良好的疾病控制。