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杂交手术顺行放置支架移植物治疗主动脉弓动脉瘤:8 例初步经验。

Hybrid procedure with antegrade stent-graft placement for aortic arch aneurysms: preliminary experience in eight patients.

机构信息

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Asanbyeongwon-gil 86, Songpa-gu, Seoul 138-736, Korea.

出版信息

J Vasc Interv Radiol. 2011 Feb;22(2):148-54. doi: 10.1016/j.jvir.2010.10.016.

Abstract

PURPOSE

To report one-stage hybrid procedures combining debranching surgery and antegrade stent-graft placement in eight patients with aortic arch aneurysms.

MATERIALS AND METHODS

Eight patients with atherosclerotic aneurysms (n = 7) or traumatic pseudoaneurysm (n = 1) were enrolled. Proximal landing zones were in zones 1 (n = 2), 2 (n = 5), and 3 (n = 1). In one zone 3 landing (distal to left subclavian artery), hybrid surgery was chosen in view of irregularity of the proximal landing zone.

RESULTS

In six patients with zone 2 and 3 landings, stent grafts were successfully placed through the surgical conduit made near the aortic root without cardiopulmonary bypass or deep hypothermic circulatory arrest. As the two patients with zone 1 involvement had an ascending aorta with a large diameter that would have required a stent graft with an oversized proximal end for safe anchoring, the proximal ascending aorta was transected, after which the stent graft was successfully placed into the transected aortic lumen; the proximal end of the stent graft was then sutured to the ascending aorta under cardiopulmonary bypass and selective cerebral perfusion. One patient died after the procedure of acute myocardial infarction. Neurologic complications occurred in three patients: one showed complete recovery and the other two showed substantial improvement. Minimal endoleak was observed at the proximal site of the stent graft in one patient.

CONCLUSIONS

The hybrid procedure with antegrade stent-graft placement is feasible for the treatment of aortic arch aneurysms. Although cardiopulmonary bypass and deep hypothermic cardiopulmonary arrest were avoided in most patients, the rate of neurologic complications suggests the need for further refinement to improve the safety of the technique.

摘要

目的

报告 8 例主动脉弓动脉瘤患者同期行血管分支重建术和顺行支架置入术的杂交手术经验。

材料与方法

共纳入 8 例患者,其中动脉粥样硬化性动脉瘤 7 例,创伤性假性动脉瘤 1 例。近端锚定区位于 1 区 2 例,2 区 5 例,3 区 1 例。由于 1 区(左锁骨下动脉远端)近端锚定区形态不规则,选择行杂交手术。

结果

2 区和 3 区的 6 例患者成功地将支架移植物经主动脉根部附近的手术通道置入,无需体外循环或深低温停循环。2 例 1 区受累患者的升主动脉直径较大,为了安全锚定需要使用近端过大的支架移植物,故先横断升主动脉,然后成功将支架移植物置入横断的主动脉腔;再在体外循环和选择性脑灌注下行近端支架移植物与升主动脉的端端吻合。1 例患者术后死于急性心肌梗死。3 例患者发生神经系统并发症:1 例完全恢复,2 例显著改善。1 例患者近端支架移植物处有轻微内漏。

结论

顺行支架置入术的杂交手术是治疗主动脉弓动脉瘤的可行方法。尽管大多数患者避免了体外循环和深低温停循环,但神经系统并发症的发生率提示需要进一步改进以提高该技术的安全性。

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