Kaji Hideko, Kaji Akira
Department of Biochemistry and Molecular Biology, Kimmel Cancer Center, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Chem Biol. 2011 Jan 28;18(1):6-7. doi: 10.1016/j.chembiol.2011.01.004.
The modification of protein by arginine catalyzed by arginyltransferases (ATE1) described by the Kashina group in this issue shows that arginylation of protein occurs widely in biology and is being recognized as a key regulatory reaction such as phosphorylation of proteins (Wang et al., 2011).
卡希纳团队在本期杂志中描述的精氨酰转移酶(ATE1)催化的蛋白质精氨酸修饰表明,蛋白质的精氨酰化在生物学中广泛存在,并被认为是一种关键的调节反应,就像蛋白质的磷酸化一样(Wang等人,2011年)。