Ben Salem H, Ouali S, Hammas S, Bougmiza I, Gribaa R, Ghannem K, Neffati E, Remadi F, Boughzela E
Service de cardiologie, hôpital universitaire Sahloul, Sousse, Tunisie.
Ann Cardiol Angeiol (Paris). 2011 Apr;60(2):87-91. doi: 10.1016/j.ancard.2010.12.014. Epub 2011 Jan 12.
To determine whether the TIMI risk score correlates with the angiographic extent and severity of coronary artery disease in patients with non-ST-elevation acute coronary syndrome undergoing cardiac catheterization.
We conducted a retrospective review of 239 medical records of patients who underwent coronary angiography secondary to non-ST-elevation acute coronary syndrome between 2002 and 2006. Patients were classified into three groups according to TIMI risk score: TIMI scores 0 to 2 (group 1: n=121), 3 to 4 (group 2: n=100), and 5 to 7 (group 3: n=18). We compared the coronary angiography findings of the three groups.
Patients of group 1 had a greater likelihood of normal or non significant CAD than patients of group 2 (36.3 % vs 13 %, P<0.001) and than patients of group 3 (36.3 % vs 0 %, P=0.002). One-vessel disease was found more often in patients with TIMI score 0 to 2 than in patients with TIMI score 5 to 7 (28.9 % vs 0 %; P=0.01), and in patients with TIMI score 3 to 4 than in those with score 5 to 7 (35 % vs 0 %, P=0.006). However, 1-vessel disease was found in patients of group 1 as often as in patients of group 2. The frequency of two-vessel disease was similar whatever the level of TIMI score was low, intermediate or high. Three-vessel or left main disease was more likely found in patients of group 3 than in patients of group 2 (66.7 % vs 26 %; P=0.01), and than patients of group 1 (66.7 % vs 13.2 %; P<0.001). Chronic coronary occlusions and coronary calcifications were also more likely found in patients with TIMI score 5 to 7.
In patients with non-ST-elevation acute coronary syndrome undergoing cardiac catheterization, the TIMI risk score correlated with the extent and severity of coronary artery disease.
确定TIMI风险评分与接受心导管检查的非ST段抬高型急性冠状动脉综合征患者冠状动脉疾病的血管造影范围及严重程度是否相关。
我们对2002年至2006年间因非ST段抬高型急性冠状动脉综合征接受冠状动脉造影的239例患者的病历进行了回顾性研究。根据TIMI风险评分将患者分为三组：TIMI评分0至2分（第1组：n = 121），3至4分（第2组：n = 100），以及5至7分（第3组：n = 18）。我们比较了三组的冠状动脉造影结果。
第1组患者冠状动脉疾病正常或不显著的可能性高于第2组患者（36.3% 对13%，P < 0.001）以及高于第3组患者（36.3% 对0%，P = 0.002）。TIMI评分0至2分的患者单支血管病变的发生率高于TIMI评分5至7分的患者（28.9% 对0%；P = 0.01），且高于TIMI评分3至4分的患者（35% 对0%，P = 0.006）。然而，第1组患者中单支血管病变的发生率与第2组患者相同。无论TIMI评分水平是低、中还是高，双支血管病变的发生率相似。第3组患者中三支血管或左主干病变的发生率高于第2组患者（66.7% 对26%；P = 0.01），且高于第1组患者（66.7% 对13.2%；P < 0.001）。TIMI评分5至7分的患者中慢性冠状动脉闭塞和冠状动脉钙化的发生率也更高。
在接受心导管检查的非ST段抬高型急性冠状动脉综合征患者中，TIMI风险评分与冠状动脉疾病的范围及严重程度相关。
