Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Czech Republic.
Fitoterapia. 2011 Jun;82(4):513-23. doi: 10.1016/j.fitote.2011.01.018. Epub 2011 Jan 28.
The interest in possible health benefits of flavonoids has increased owing to their potent antioxidant and free radical scavenging activities observed in vitro. Nevertheless, the antioxidant efficacy of flavonoids in vivo is less documented and their prooxidant properties have been actually described in vivo. Due to their prooxidant properties, they are able to cause oxidative damage by reacting with various biomolecules, such as lipids, proteins and DNA. Hence, the aim of this review is to discuss both the antioxidant and prooxidant effects of flavonoids.
由于在体外观察到类黄酮具有强大的抗氧化和清除自由基活性，因此人们对其可能对健康有益的兴趣日益增加。然而，类黄酮在体内的抗氧化功效的记录较少，实际上在体内已经描述了它们的促氧化剂特性。由于其促氧化剂特性，它们能够通过与各种生物分子（如脂质、蛋白质和 DNA）反应而引起氧化损伤。因此，本综述的目的是讨论类黄酮的抗氧化和促氧化剂作用。
