Butler A R, Horii S C, Kricheff I I, Shannon M B, Budzilovich G N
Radiology. 1978 Nov;129(2):433-9. doi: 10.1148/129.2.433.
Four histopathological indices of malignancy--cellularity, pleomorphism, vascularity, and necrosis--were correlated with the positive-contrast CT scan in 84 patients with pathologically proved astrocytoma. Vascularity and necrosis correlated best with the scan in supratentorial tumors, while vascularity and cellularity correlated significantly with the scan in cerebellar astrocytomas. These findings indicate that the degree of malignancy of a supratentorial astrocytoma can be inferred from the contrast-enhanced scan, but that this is not generally possible with posterior fossa tumors.
对84例经病理证实为星形细胞瘤的患者，将四种恶性肿瘤的组织病理学指标——细胞密度、多形性、血管分布及坏死情况——与阳性对比CT扫描结果进行相关性分析。幕上肿瘤中，血管分布及坏死情况与扫描结果的相关性最佳，而在小脑星形细胞瘤中，血管分布及细胞密度与扫描结果显著相关。这些发现表明，幕上星形细胞瘤的恶性程度可通过增强扫描推断，但后颅窝肿瘤一般无法做到。
