Piccinno R, Menni S, Cavicchini S, Gianotti R
Istituto di Clinica Dermatologica I e Dermatologia Pediatrica, Università degli Studi di Milano.
G Ital Dermatol Venereol. 1990 Oct;125(10):449-51.
The Authors describe the case of a woman affected by generalized plane xanthoma and IgG multiple myeloma with k type immunoglobulins. The association between the two affections is well known. The antilipoprotein activity of the paraprotein has been proved in some cases, associated or not to hyperlipemia. The pathogenetic mechanism of plane xanthoma formation is described briefly. The possible occurrence of plane xanthoma with multiple myeloma is stressed, along with the possible association with other systemic diseases.
作者描述了一名患有泛发性扁平黄瘤和IgG k型免疫球蛋白多发性骨髓瘤的女性病例。这两种病症之间的关联是众所周知的。在一些病例中,已证实副蛋白具有抗脂蛋白活性,无论是否伴有高脂血症。简要描述了扁平黄瘤形成的发病机制。强调了扁平黄瘤与多发性骨髓瘤同时出现的可能性,以及与其他全身性疾病的可能关联。