Alonso Faustino Tomás, Garmendia María Luisa, Aguirre Magdalena de, Searle Javier
División Epidemiología, Escuela de salud Pública, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Rev Med Chil. 2010 Oct;138(10):1253-8. Epub 2011 Jan 10.
There is a worldwide tendency towards a reduction in the rates of deaths due to cirrhosis. In Chile, a decrease in the number of hospital admissions due to this disease has been recorded.
To assess general characteristics and temporal evolution of liver cirrhosis mortality in Chile between 1990 and 2007.
National death records and population databases were reviewed. Crude and age-adjusted mortality rates for alcoholic and non-alcoholic cirrhosis were calculated, evaluating their evolution in the study period and the relative risk by gender.
In the study period, 44,894 deaths caused by cirrhosis were recorded. Mortality rate was 16.6 deaths per 100,000 inhabitants. 54% of deaths were attributed to non-alcoholic cirrhosis. There was a reduction in mortality rates for both types of cirrhosis. Males accounted for 83 and 65% of deaths caused by alcoholic and non-alcoholic cirrhosis, respectively. The figures for relative risk of death were 5 and 1.9, respectively.
Alcoholic cirrhosis was the preponderant cause among liver cirrhosis deaths. A decrease in mortality rates was observed in the study period. Improvements in disease treatment and control could possibly explain this trend.
全球范围内肝硬化死亡率呈下降趋势。在智利，因该疾病住院的人数已有所减少。
评估1990年至2007年期间智利肝硬化死亡率的总体特征和时间演变情况。
查阅了国家死亡记录和人口数据库。计算了酒精性和非酒精性肝硬化的粗死亡率和年龄调整死亡率，评估了它们在研究期间的演变情况以及按性别划分的相对风险。
在研究期间，记录了44,894例由肝硬化导致的死亡。死亡率为每10万居民中有16.6例死亡。54%的死亡归因于非酒精性肝硬化。两种类型的肝硬化死亡率均有所下降。男性分别占酒精性和非酒精性肝硬化所致死亡的83%和65%。死亡相对风险数字分别为5和1.9。
酒精性肝硬化是肝硬化死亡的主要原因。在研究期间观察到死亡率有所下降。疾病治疗和控制的改善可能解释了这一趋势。
