School of Medicine, Universidad Católica Santo Toribio de Mogrovejo, Chiclayo 14012, Peru.
Asociación Científica Médico Estudiantil USAT, Chiclayo 14012, Peru.
Int J Environ Res Public Health. 2022 Jul 25;19(15):9036. doi: 10.3390/ijerph19159036.
Liver cirrhosis (LC) is an irreversible, chronic disease and constitutes the last clinical stage of many different liver diseases. The main cause of death is upper gastrointestinal bleeding caused by esophageal variceal rupture. We aim to depict the trend and estimate the morbimortality. For this, we conducted an ecological study and analyzed data from 2004-2016 using the public information provided by the Peruvian Ministry of Health (Ministerio de Salud del Perú, MINSA). Morbidity and mortality were presented according to 5-year groups. Regions were divided according to age quintiles for each studied year, and standardized morbidity and mortality rates were calculated for each natural geographic region; we found that LC-related morbidity per 100,000 people was 52.3 in 2004 and 117.9 in 2016. LC-related mortality had increased from 13.6 deaths per 100,000 people in 2004-2005 to 16.8 deaths per 100,000 people in 2015-2016. Morbidity showed an upward trend in Peru, especially in the departments of Callao, Ica, and Tumbes, whereas mortality showed an upward trend in the departments of Lambayeque, Ica, and Callao.
肝硬化（LC）是一种不可逆转的慢性疾病，是许多不同肝病的终末临床阶段。主要死亡原因是食管静脉曲张破裂引起的上消化道出血。我们旨在描述趋势并估计发病率和死亡率。为此，我们进行了一项生态学研究，使用秘鲁卫生部（MINSA）提供的公共信息分析了 2004-2016 年的数据。发病率和死亡率根据 5 年组呈现。根据每年研究的年龄五分位数对地区进行了划分，并为每个自然地理区域计算了标准化发病率和死亡率；我们发现，2004 年每 10 万人中有 52.3 人患有与 LC 相关的疾病，而 2016 年则为 117.9 人。与 LC 相关的死亡率从 2004-2005 年的每 10 万人中有 13.6 人死亡上升到 2015-2016 年的每 10 万人中有 16.8 人死亡。秘鲁的发病率呈上升趋势，尤其是在卡亚俄、伊卡和通贝斯地区，而死亡率呈上升趋势的是兰巴耶克、伊卡和卡亚俄地区。
