Can Fam Physician. 1983 Aug;29:1445-50.
A cohort study was undertaken to see if the frequency of office reported illness during the three weeks after MMR immunization was greater among Indian children (N=127) compared to non-Indian children (N=81) attending a family practice centre. All children had been given HPV(77)DE(5) vaccine or RA 27/3 vaccine between ages 11 and 24 months. Illness after immunization was not related to frequency of attendance at the medical centre or weight at age 12 months. The overall illness rate for Indian children was almost twice the rate for non-Indians. Indian children who were ill before immunization were more likely to be ill during the three week post-MMR period. No such relationship was noted among non-Indian children. This suggests that children with an established record of frequent illness are likely to experience an illness following MMR immunization. These results need to be confirmed by a prospective study.
一项队列研究旨在观察在接受 MMR 免疫接种后的三周内，在家庭医疗中心就诊的印度儿童（N=127）与非印度儿童（N=81）相比，报告疾病的频率是否更高。所有儿童均在 11 至 24 个月大时接种了 HPV(77)DE(5)疫苗或 RA 27/3 疫苗。接种疫苗后的疾病与就诊频率或 12 个月时的体重无关。印度儿童的整体疾病发病率几乎是非印度儿童的两倍。在免疫接种前生病的印度儿童在 MMR 接种后的三周内更有可能生病。在非印度儿童中未发现这种关系。这表明，有频繁疾病记录的儿童在接受 MMR 免疫接种后可能会出现疾病。这些结果需要通过前瞻性研究来证实。
