Savary D L, Garon A
Can Fam Physician. 1983 Sep;29:1627-30.
Constipation is an important problem in older patients, who are often chronic users of laxatives. Dietary fiber is becoming more important in treating gastrointestinal disorders. In studying the drug profiles of 52 elderly patients in a chronic care unit, we found that a large percentage were taking laxatives. We therefore wanted to compare the effect of a diet enriched with bran to the effect of an emollient laxative, docusate sodium. Patients were divided into two groups. For the first three weeks, one group received a diet with 15 g/day natural wheat bran added, plus a placebo, and the other received 200 mg/day docusate sodium. In the second three weeks, the groups were switched to the other treatment. After the 42 days of the study, the number of stools per day per patient did not differ significantly, whether they had been taking bran or laxatives. Otherwise, transit times revealed that those who had taken bran had a more rapid transit time than those who had taken laxatives. These results show the efficacy of dietary fiber, particularly wheat bran, in prevention and correction of constipation in the elderly.
便秘是老年患者的一个重要问题，这些患者常长期使用泻药。膳食纤维在治疗胃肠道疾病中变得越来越重要。在研究一家慢性病护理机构中52名老年患者的用药情况时，我们发现很大一部分患者正在服用泻药。因此，我们想比较富含麸皮的饮食与缓泻剂多库酯钠的效果。患者被分为两组。在前三周，一组接受添加了每日15克天然麦麸的饮食，外加一种安慰剂，另一组接受每日200毫克多库酯钠。在接下来的三周，两组互换治疗方式。在为期42天的研究结束后，每位患者每天的排便次数并无显著差异，无论他们服用的是麸皮还是泻药。此外，转运时间显示，服用麸皮的患者比服用泻药的患者转运时间更快。这些结果表明膳食纤维，尤其是麦麸，在预防和纠正老年人便秘方面的功效。
