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Sitagliptin manufacture: a compelling tale of green chemistry, process intensification, and industrial asymmetric catalysis.

作者信息

Desai Aman A

机构信息

Process Chemistry and Development, Core R & D, The Dow Chemical Company, Midland, MI 48674, USA.

出版信息

Angew Chem Int Ed Engl. 2011 Feb 25;50(9):1974-6. doi: 10.1002/anie.201007051. Epub 2011 Jan 31.

DOI:10.1002/anie.201007051

PMID:21284073

Abstract

摘要

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Angew Chem Int Ed Engl. 2011 Feb 25;50(9):1974-6. doi: 10.1002/anie.201007051. Epub 2011 Jan 31.

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture.

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Sitagliptin manufacture: a compelling tale of green chemistry, process intensification, and industrial asymmetric catalysis.

作者信息

Desai Aman A

机构信息

Process Chemistry and Development, Core R & D, The Dow Chemical Company, Midland, MI 48674, USA.

出版信息

Angew Chem Int Ed Engl. 2011 Feb 25;50(9):1974-6. doi: 10.1002/anie.201007051. Epub 2011 Jan 31.

DOI:10.1002/anie.201007051

PMID:21284073

Abstract

摘要

相似文献

Sitagliptin manufacture: a compelling tale of green chemistry, process intensification, and industrial asymmetric catalysis.

Angew Chem Int Ed Engl. 2011 Feb 25;50(9):1974-6. doi: 10.1002/anie.201007051. Epub 2011 Jan 31.

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture.

Science. 2010 Jul 16;329(5989):305-9. doi: 10.1126/science.1188934. Epub 2010 Jun 17.

Sitagliptin.

Nat Rev Drug Discov. 2007 Feb;6(2):109-10. doi: 10.1038/nrd2245.

Sitagliptin/metformin (Janumet) for type 2 diabetes.

Med Lett Drugs Ther. 2007 Jun 4;49(1262):45-7.

(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

Bioorg Med Chem Lett. 2007 Jan 1;17(1):49-52. doi: 10.1016/j.bmcl.2006.09.099. Epub 2006 Oct 5.

[Sitagliptin].

Rev Infirm. 2008 Oct(144):46-8.

Sitagliptin combined with sulphonylureas: new indication. Other treatments are preferable.

Prescrire Int. 2009 Feb;18(99):14-5.

Severe leucopenia associated with Sitagliptin use.

Diabetes Res Clin Pract. 2011 Feb;91(2):e30-2. doi: 10.1016/j.diabres.2010.10.004. Epub 2010 Oct 29.

[Sitagliptin. Dipeptidylpeptidase 4 inhibitor for patients with diabetes mellitus type 2].

Med Monatsschr Pharm. 2007 Aug;30(8):282-6; quiz 287-8.

[Incretin strategy in the treatment of type 2 diabetes mellitus--the DPP-IV inhibitor sitagliptin].

Vnitr Lek. 2007 Oct;53(10):1109-13.

引用本文的文献

Advances in the Molecular Modification of Microbial ω-Transaminases for Asymmetric Synthesis of Bulky Chiral Amines.

Microorganisms. 2025 Apr 3;13(4):820. doi: 10.3390/microorganisms13040820.

COFcap2, a recyclable tandem catalysis reactor for nitrogen fixation and conversion to chiral amines.

Nat Commun. 2025 Jan 24;16(1):992. doi: 10.1038/s41467-025-56214-0.

A Dual Role for the -Perfluorobutanesulfinamide Auxiliary in an Asymmetric Decarboxylative Mannich Reaction.

Org Lett. 2024 Oct 18;26(41):8810-8815. doi: 10.1021/acs.orglett.4c03139. Epub 2024 Sep 30.

Enzymatic Routes for Chiral Amine Synthesis: Protein Engineering and Process Optimization.

Biologics. 2024 Jun 25;18:165-179. doi: 10.2147/BTT.S446712. eCollection 2024.

Current status and emerging frontiers in enzyme engineering: An industrial perspective.

Heliyon. 2024 Jun 7;10(11):e32673. doi: 10.1016/j.heliyon.2024.e32673. eCollection 2024 Jun 15.

An Extremely Sensitive Ultra-High Throughput Growth Selection Assay for the Identification of Amidase Activity.

Appl Microbiol Biotechnol. 2024 Jun 24;108(1):392. doi: 10.1007/s00253-024-13233-z.

Recombinant Amidases: Recent Insights and its Applications in the Production of Industrially Important Fine Chemicals.

Mol Biotechnol. 2025 Mar;67(3):910-924. doi: 10.1007/s12033-024-01123-8. Epub 2024 Apr 10.

Supramolecular Ionic Liquid Gels for Enzyme Entrapment.

ACS Sustain Chem Eng. 2023 Apr 24;11(18):6829-6837. doi: 10.1021/acssuschemeng.3c00517. eCollection 2023 May 8.

Thermostable enzyme research advances: a bibliometric analysis.

J Genet Eng Biotechnol. 2023 Mar 27;21(1):37. doi: 10.1186/s43141-023-00494-w.

Enzymatic and chemo-enzymatic strategies to produce highly valuable chiral amines from biomass with ω-transaminases on 2D zeolites.

Natl Sci Rev. 2022 Jul 29;9(9):nwac135. doi: 10.1093/nsr/nwac135. eCollection 2022 Sep.