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热稳定酶研究进展:文献计量分析

Thermostable enzyme research advances: a bibliometric analysis.

作者信息

Che Hussian Che Haznie Ayu, Leong Wai Yie

机构信息

INTI International University & Colleges, Nilai, Negeri Sembilan, Malaysia.

出版信息

J Genet Eng Biotechnol. 2023 Mar 27;21(1):37. doi: 10.1186/s43141-023-00494-w.

Abstract

Thermostable enzymes are enzymes that can withstand elevated temperatures as high as 50 °C without altering their structure or distinctive features. The potential of thermostable enzymes to increase the conversion rate at high temperature has been identified as a key factor in enhancing the efficiency of industrial operations. Performing procedures at higher temperatures with thermostable enzymes minimises the risk of microbial contamination, which is one of the most significant benefits. In addition, it helps reduce substrate viscosity, improve transfer speeds, and increase solubility during reaction operations. Thermostable enzymes offer enormous industrial potential as biocatalysts, especially cellulase and xylanase, which have garnered considerable amount of interest for biodegradation and biofuel applications. As the usage of enzymes becomes more common, a range of performance-enhancing applications are being explored. This article offers a bibliometric evaluation of thermostable enzymes. Scopus databases were searched for scientific articles. The findings indicated that thermostable enzymes are widely employed in biodegradation as well as in biofuel and biomass production. Japan, the United States, China, and India, as along with the institutions affiliated with these nations, stand out as the academically most productive in the field of thermostable enzymes. This study's analysis exposed a vast number of published papers that demonstrate the industrial potential of thermostable enzymes. These results highlight the significance of thermostable enzyme research for a variety of applications.

摘要

热稳定酶是指能够承受高达50°C的高温而不改变其结构或独特特性的酶。热稳定酶在高温下提高转化率的潜力已被确定为提高工业生产效率的关键因素。使用热稳定酶在更高温度下进行操作可将微生物污染的风险降至最低,这是最显著的好处之一。此外,它有助于降低底物粘度、提高转移速度并在反应操作过程中增加溶解度。热稳定酶作为生物催化剂具有巨大的工业潜力,尤其是纤维素酶和木聚糖酶,它们在生物降解和生物燃料应用方面引起了相当大的关注。随着酶的使用变得越来越普遍,人们正在探索一系列提高性能的应用。本文对热稳定酶进行了文献计量评估。在Scopus数据库中搜索了科学文章。研究结果表明,热稳定酶广泛应用于生物降解以及生物燃料和生物质生产。日本、美国、中国和印度以及与这些国家相关的机构在热稳定酶领域的学术产出最为突出。这项研究的分析揭示了大量已发表的论文,这些论文证明了热稳定酶的工业潜力。这些结果凸显了热稳定酶研究在各种应用中的重要性。

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