骶神经刺激对肛肠功能障碍的影响。
The influence of sacral nerve stimulation on anorectal dysfunction.
机构信息
Academic Surgical Unit, Centre for Digestive Diseases, Blizard Institute of Cellular and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary University London, London, UK.
出版信息
Colorectal Dis. 2011 Mar;13 Suppl 2:5-9. doi: 10.1111/j.1463-1318.2010.02518.x.
AIM
Sacral nerve stimulation (SNS) has become an established option in the management of defaecatory disorders. There are many data on the end-organ effects of SNS, but limited consensus on its mechanism of action. The objective of this review was to determine the effect of sacral nerve stimulation (SNS) on anorectal function.
METHOD
Systematic literature review of the effect of sacral nerve stimulation (SNS) on anorectal function.
RESULTS
There was significant heterogeneity of data pertaining to the effects of SNS on anorectal function, with no consistent change in physiological measures identified. Most data supported a mixed mechanism of action on anal motor and rectal sensory functioning.
CONCLUSION
To date, conflicting data exist on the mechanism of action of SNS as determined by end-organ changes in anorectal physiology. Nevertheless, the data as they stand best support a mixed mechanism of action on anal motor and rectal sensory functions.
目的
骶神经刺激（SNS）已成为治疗排便障碍的一种既定选择。有许多关于 SNS 终末器官效应的数据，但对其作用机制尚无共识。本综述的目的是确定骶神经刺激（SNS）对肛门直肠功能的影响。
方法
对骶神经刺激（SNS）对肛门直肠功能影响的系统文献复习。
结果
SNS 对肛门直肠功能影响的数据存在显著的异质性，未确定生理测量的一致性变化。大多数数据支持对肛门运动和直肠感觉功能的混合作用机制。
结论
迄今为止，通过肛门直肠生理学的终末器官变化来确定 SNS 的作用机制存在相互矛盾的数据。尽管如此，目前的数据最好支持对肛门运动和直肠感觉功能的混合作用机制。
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