Department of Radiology, Nuclear Medicine Service, University Hospital, UMDNJ, Newark, NJ 07103, USA.
Clin Nucl Med. 2011 Mar;36(3):227-8. doi: 10.1097/RLU.0b013e318208f503.
Superscans on bone scintigraphy have been described mostly in metastatic and metabolic bone diseases, with different patterns and appearances of radiotracer uptake. This is a report of bone scintigraphy demonstrating superimposed metastatic and metabolic superscan in a patient with prostate cancer, who subsequently developed renal osteodystrophy. Two years after the first bone scintigraphy showing multiple metastases, the patient developed renal insufficiency, hyperphosphoremia, and hypocalcemia. Repeat bone scintigraphy demonstrates significantly different appearance from that of the first study. Caution should be exercised when interpreting a bone scintigraphy in patients with known malignancy and coexisting renal failure or metabolic bone disease. Superimposed appearances of metastatic and metabolic superscan may obscure recognition of osseous metastases.
骨闪烁扫描术上的超级影像大多见于转移性和代谢性骨疾病，其放射性示踪剂摄取呈现不同的模式和外观。这是一例前列腺癌患者的骨闪烁扫描术报告，该患者随后发展为肾性骨营养不良。首次骨闪烁扫描术显示多发性转移后两年，患者出现肾功能不全、高磷血症和低钙血症。重复骨闪烁扫描术显示出与第一次研究明显不同的外观。在已知患有恶性肿瘤且同时伴有肾衰竭或代谢性骨疾病的患者中，对骨闪烁扫描术的解释应谨慎。转移性和代谢性超级影像的叠加可能会掩盖对骨转移的识别。
