Los Angeles, Calif.; and Nasser City, Sohag, Egypt From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of California, Los Angeles Medical Center; the Department of Plastic and Reconstructive Surgery, Sohag University School of Medicine; and the University of California, Los Angeles School of Dentistry.
Plast Reconstr Surg. 2011 Feb;127(2):812-821. doi: 10.1097/PRS.0b013e318200aa08.
Given the multiple permutations in craniofacial malformations, classification of median craniofacial dysplasia or midline Tessier no. 0 to 14 clefts has been difficult and disjointed. In this review, the authors present a summary of normal embryology, prior terminology, and their proposed new classification system. Median craniofacial dysplasia has tissue agenesis and holoprosencephaly at one end (the hypoplasias), frontonasal hyperplasia and excessive tissue (the hyperplasias) at the other end, and abnormal splitting or clefting and normal tissue volume (dysraphia) occupying the middle portion of the spectrum. These three distinct subclassifications have different forms of anomalies within their groups.
鉴于颅面畸形的多种排列，中线颅面发育不良或中线 Tessier 0 至 14 裂隙的分类一直很困难且不连贯。在这篇综述中，作者总结了正常胚胎发生、先前的术语以及他们提出的新分类系统。中线颅面发育不良在一端（发育不良）具有组织发育不全和全前脑，在另一端（增生）具有前鼻突过度增生和过多的组织，以及中间部分具有异常分裂或裂隙和正常组织体积（发育不良）。这三个不同的细分分类在其组内具有不同形式的异常。
