G蛋白及G蛋白亚基在信号转导中的作用。
Roles of G proteins and G protein subunits in signal transduction.
作者信息
Iyengar R, Birnbaumer L
机构信息
Department of Pharmacology, Mount Sinai School of Medicine, New York, NY 10029.
出版信息
Lymphokine Res. 1990 Winter;9(4):533-7.
PMID:2128642
Abstract
General features of signal transduction by G proteins are described. Recent results on roles of beta gamma dimers, kinetic properties of Gi alpha subunits, structural diversity of Go alpha subunits and possible functions of the Go protein as a stimulator of phospholipase C activity are discussed.
摘要
描述了G蛋白信号转导的一般特征。讨论了βγ二聚体的作用、Giα亚基的动力学特性、Goα亚基的结构多样性以及Go蛋白作为磷脂酶C活性刺激剂的可能功能的最新研究结果。
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