Department of Anesthesiology and Pain Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.
Korean J Anesthesiol. 2010 Dec;59 Suppl(Suppl):S53-7. doi: 10.4097/kjae.2010.59.S.S53. Epub 2010 Dec 31.
The infiltration of dilute epinephrine solution has been used for many years to provide hemostasis. However, epinephrine has adverse cardiovascular effects, such as arrhythmia, pulmonary edema, and even cardiac arrest. We have experienced epinephrine-induced cardiovascular crisis, with severe hypertension, tachycardia, and cardiac arrest after subcutaneous infiltration of a 2% lidocaine and 1 : 200,000 epinephrine solution in a patient with an asymptomatic subarachnoid hemorrhage. We provided successfully advanced cardiac life support in the operating room and cardioverted the patient back into a sinus rhythm with no untoward effects. The patient recovered without any apparent sequelae after intensive care.
多年来，人们一直使用稀释肾上腺素溶液进行浸润注射以达到止血目的。然而，肾上腺素会产生不良的心血管效应，如心律失常、肺水肿，甚至心跳骤停。我们曾遇到过一例因蛛网膜下腔出血行 2%利多卡因和 1:200000 肾上腺素溶液皮下浸润注射后发生肾上腺素诱导的心血管危象，患者出现严重高血压、心动过速，甚至心跳骤停。我们在手术室成功地提供了高级心脏生命支持，并通过电复律将患者恢复为窦性心律，无不良反应。患者在重症监护后恢复良好，无明显后遗症。
