[从患有不同形式成血病的患者所获悬浮细胞系中分离出爱泼斯坦-巴尔病毒]
[Isolation of the Epstein-Barr virus in suspension cell lines obtained from persons with different forms of hemoblastosis].
作者信息
Agrba V Z, Iakovleva L A, Lapin B A, Lebedev V N, Grigor'ev A S
出版信息
Vopr Onkol. 1978;24(9):33-40.
PMID:212872
Abstract
Isolation of EBV from patients with different types of haemoblastosis by establishing virus-producing cell lines is described. EBV was isolated from patients with myelogenous leukemia in 71%, Hodgkin's disease--in 22%. EBV was also isolated from 1 patient with lung tumor and leukemogenic reaction. All 8 established cell lines produced EBV in 0.5--3% of cells. The cells of the lines concerned are lymphoblasts and show B-cell characteristics.
摘要
本文描述了通过建立产病毒细胞系从不同类型成血细胞增多症患者中分离出EB病毒（Epstein-Barr virus，EBV）的方法。EBV从71%的髓性白血病患者、22%的霍奇金病患者中分离得到。EBV也从1例患有肺肿瘤并伴有致白血病反应的患者中分离得到。所有8个建立的细胞系中，有0.5% - 3%的细胞产生EBV。相关细胞系的细胞为成淋巴细胞，并表现出B细胞特征。
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