State Key Laboratory for Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Biol Trace Elem Res. 2011 Dec;143(3):1480-8. doi: 10.1007/s12011-011-8981-5. Epub 2011 Feb 3.
Forty-eight 2-year-old Liaoning Cashmere goats (body weight = 38.0 ± 2.94 kg) were used to investigate the effects of dietary iodine (I) and selenium (Se) supplementation on nutrient digestibility, serum thyroid hormones, and antioxidant status during the cashmere telogen period to learn more about the effects of dietary I and Se on nutrition or health status of Cashmere goats. The goats were equally divided into six groups of eight animals each that were treated with 0, 2, or 4 mg of supplemental I/kg dry matter (DM) and 0 or 1 mg of supplemental Se/kg DM in a 2 × 3 factorial arrangement of treatments. The six treatments were I(0)Se(0), I(2)Se(0), I(4)Se(0), I(0)Se(1), I(2)Se(1), and I(4)Se(1). The concentrations of I and Se in the basal diet were 0.67 and 0.09 mg/kg DM, respectively. The study started in March and proceeded for 45 days. Supplemental I or Se alone had no effect on nutrient digestibility and nitrogen metabolism. However, the interaction between I and Se was significant regarding the digestibility of acid detergent fiber (ADF; P < 0.05), and compared with group I(4)Se(1), the digestibility of ADF was significantly increased in group I(4)Se(0) (P < 0.05). Selenium supplementation did not affect serum triiodothyronine (T(3)) or thyroxine (T(4)) concentrations. However, the concentration of serum T(4) but not that of T(3) was significantly increased with I supplementation (P < 0.05). In addition, serum superoxide dismutase (SOD) activity was not affected (P > 0.05), but serum glutathione peroxidase (GSH-Px) activity was significantly decreased by I supplementation (P < 0.05). The antioxidant status was improved by Se supplementation, and the activities of SOD and GSH-Px were significantly increased (P < 0.05).
48 只 2 岁辽宁绒山羊（体重=38.0±2.94kg）用于研究日粮碘（I）和硒（Se）补充对绒毛休止期绒山羊养分消化率、血清甲状腺激素和抗氧化状态的影响，以了解日粮 I 和 Se 对绒山羊营养或健康状况的影响。将这些山羊等分为 6 组，每组 8 只，分别用 0、2 或 4mg/kg 干物质（DM）的补充 I 和 0 或 1mg/kg DM 的补充 Se 进行处理，采用 2×3 因子试验设计。这 6 种处理分别为 I(0)Se(0)、I(2)Se(0)、I(4)Se(0)、I(0)Se(1)、I(2)Se(1)和 I(4)Se(1)。基础日粮中 I 和 Se 的浓度分别为 0.67 和 0.09mg/kg DM。该研究于 3 月开始，持续 45 天。单独补充 I 或 Se 对养分消化率和氮代谢没有影响。然而，I 和 Se 之间存在显著的互作效应，会影响酸性洗涤纤维（ADF）的消化率（P<0.05），与 I(4)Se(1)组相比，I(4)Se(0)组的 ADF 消化率显著提高（P<0.05）。Se 补充不影响血清三碘甲状腺原氨酸（T(3)）或甲状腺素（T(4)）浓度。然而，I 补充会显著增加血清 T(4)的浓度（P<0.05），但 T(3)的浓度没有变化。此外，血清超氧化物歧化酶（SOD）活性不受影响（P>0.05），但 I 补充会显著降低血清谷胱甘肽过氧化物酶（GSH-Px）活性（P<0.05）。Se 补充改善了抗氧化状态，SOD 和 GSH-Px 的活性显著增加（P<0.05）。
