Tulane School of Medicine, Department of Obstetrics and Gynecology, SL-11, Section of Maternal-Fetal Medicine, 1430 Tulane Ave, New Orleans, LA 70112, USA.
J Natl Med Assoc. 2010 Dec;102(12):1158-64. doi: 10.1016/s0027-9684(15)30770-7.
To describe the obstetrical characteristics of women without prenatal care and/or undocumented human immunodeficiency virus (HIV) serostatus who presented for delivery and to assess the usefulness of rapid HIV screening in these women.
The study design was a retrospective analysis. Demographics, labor, delivery characteristics, and pregnancy outcomes of women without prenatal care and/or unknown HIV serostatus were reviewed.
Three hundred fifty parturients met the inclusion criteria: 15.2% presented at complete cervical dilation, 48.6% with cervical dilation of at least 5 cm, and 43.1% with ruptured membranes. Twenty-two percent of parturients delivered within 1 hour of admission, 47.6% delivered within 4 hours of admission, and 5.5% delivered prior to arrival to the hospital. With the lengthy admission process and procurement of zidovudine from the pharmacy requiring at least 1 hour at best, 27.5% would not have the benefit of intrapartum zidovudine treatment. Single Use Diagnostic System HIV-1 rapid test was reactive and confirmed in 7 women (2.5%).
Rapid HIV screening is a useful tool for guiding immediate obstetrical management and coordinated care for the neonate. In some circumstances, the full benefit of rapid HIV detection will not be realized due to advanced labor, ruptured members, or delivery prior to arrival.
描述未接受产前护理和/或未进行人类免疫缺陷病毒(HIV)血清学检测的产妇的分娩特点,并评估快速 HIV 筛查在这些产妇中的应用价值。
研究设计为回顾性分析。回顾了未接受产前护理和/或 HIV 血清学未知的产妇的人口统计学、分娩特征和妊娠结局。
350 名产妇符合纳入标准:15.2%的产妇宫口完全扩张,48.6%的产妇宫口扩张至少 5cm,43.1%的产妇胎膜破裂。22%的产妇在入院后 1 小时内分娩,47.6%的产妇在入院后 4 小时内分娩,5.5%的产妇在到达医院前分娩。由于入院流程较长,且从药房采购齐多夫定最快需要 1 小时,27.5%的产妇将无法接受产时齐多夫定治疗。一次性使用诊断系统 HIV-1 快速检测呈阳性反应,并在 7 名妇女(2.5%)中得到确认。
快速 HIV 筛查是指导即时产科管理和新生儿协调护理的有用工具。在某些情况下,由于产程进展、胎膜破裂或在到达医院前分娩,快速 HIV 检测的全部益处可能无法实现。