Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Pediatr Res. 2011 May;69(5 Pt 2):63R-8R. doi: 10.1203/PDR.0b013e318212c2b3.
Magnetic resonance (MR) examination provides a powerful tool for investigating brain structural changes in children with autism spectrum disorder (ASD). We review recent advances in the understanding of structural MR correlates of ASD. We summarize findings from studies based on voxel-based morphometry, surface-based morphometry, tensor-based morphometry, and diffusion-tensor imaging. Finally, we discuss diagnostic models of ASD based on MR-derived features.
磁共振(MR)检查为研究自闭症谱系障碍(ASD)儿童的大脑结构变化提供了有力工具。我们综述了有关 ASD 的结构磁共振相关研究的最新进展。我们总结了基于体素形态计量学、基于表面形态计量学、张量形态计量学和弥散张量成像的研究结果。最后,我们讨论了基于 MR 特征的 ASD 诊断模型。