Can Fam Physician. 1982 Jan;28:105-9.
Neuroleptics are antipsychotic drugs. In addition to their antipsychotic properties, many physicians use them as anti-anxiety or antiemetics. Indeed, most patients referred to psychiatrists would have been given one, or a combination, of these drugs. Physicians should therefore be aware of their side-effects. Abnormal involuntary movements, now recognized as side-effects of neuroleptics, are broadly classified as acute early occurring movement disorders and late appearing movement disorders. The clinical description, early recognition, pathophysiology, prevention and treatment of these side-effects are reviewed and judicious use of these drugs advocated.
神经阻滞剂是抗精神病药物。除了具有抗精神病作用外,许多医生还将其用作抗焦虑药或止吐药。实际上,大多数被转介给精神科医生的患者都曾使用过这些药物中的一种或几种。因此,医生应该了解它们的副作用。现在已经认识到,异常不随意运动是神经阻滞剂的副作用,它们被广泛分为急性早期发生的运动障碍和迟发性运动障碍。本文回顾了这些副作用的临床描述、早期识别、病理生理学、预防和治疗,并提倡合理使用这些药物。